Anti-Muller Hormone (AMH)

 

In the life of each couple, a moment comes when a man and a woman consider family planning. For some who have achieved results quickly enough, this period is associated with an exciting anticipation of a positive pregnancy test result, and for others with a long process filled with disappointment.

While identifying the possible reasons of infertility, fertility specialists prescribe a test to determine the level of the hormonal background of a woman already on the first stage of preparation. If the results of the standard test do not go beyond the limits of the norm and do not allow to establish the cause of infertility, a test for the level of Anti-Muller Hormone (AMG) is assigned.

Anti-pulmonary hormone (Anti-Muller Hormone) is one of the most important hormones that affects fertility. It plays a key role in the differentiation of primary sexual characteristics in the prenatal period.

This compound protein got its name from the name of the German biologist and naturalist Johann Muller, who for the first time derived a common canal-tube from the female and male embryos - the Muller stream. Thanks to AMH, in the sixth week of pregnancy, the formation of the Mullerian flow of the vagina, fallopian tube and uterus takes place in female embryos and prostatic uterus and epididymis in male embryos.

Anti-Muller hormone in women is produced by the cells of the ovaries, starting from the period of maturation of the follicles. It can only be determined from the beginning of puberty until the onset of menopause. A woman’s hormone level in the blood indicates her ovarian reserve and fertility.

Venous blood sampling is used to determine the level of AMG. For an objective analysis the blood should be donated in the morning on an empty stomach on the 2-5 day of the menstrual cycle. If there is no menstrual cycle, the sampling is conducted any day. Before the examination for several days it is necessary to limit the emotional and physical loads as much as possible. Having the test during the exacerbation of chronic diseases and acute infectious and inflammatory diseases (ARVI, flu, etc.) is highly undesirable.

AMH level for women:

Low 0.01 - 0.9 ng / ml

Medium 1.0 - 2.5 ng / ml

High More than 2.5 ng / ml

Normally, the maximum content of AMH is observed in women aged 20 to 30 years, that is, at the peak of female fertility.

The test for the level of anti-Muller hormone in women`s organism is informative in case of:

  • premature puberty;
  • premature menopause;
  • infertility;
  • decrease in ovarian reserve;
  • polycystic ovaries;
  • granular ovarian tumors;
  • obesity in late reproductive age.

Today the AMH test is the most accurate indicator of ovarian reserve for women of reproductive age. Low hormone levels also indicate the ineffectiveness of therapy in the frame of infertility treatment.

 

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