Electron microscopic examination of sperm (EMIS)

 

Electron microscopic examination of sperm is an electronic diagnostic test, which allows to evaluate the qualitative and quantitative characteristics of male gametes in the ejaculate using multiple optical zoom. The test is carried out using an electron microscope capable of zooming the material under investigation in a million times. This immense technique makes it possible to analyze the intracellular structures of male germ cells, which is impossible using any other study (MAR test, spermogram).

To draw conclusions on the qualitative and quantitative state of biological material, analysis of 45 indicators is done. The most significant stages of the study are:

  • core characteristics (form, quality);
  • study of the shape of the axial filament of the flagellum;
  • study of the structure of the outer ring fibrils;
  • analysis of the structure of mitochondria;
  • establishment of dislocation of cytoplasmic drops;
  • description of acrosome (presence, size, characteristic);
  • characteristic of dense fibrous membrane (density, structure);
  • a description of the form of centrioles;
  • detection and analysis of genetic pathologies;
  • determining the presence of abnormal cells, bacteria and viruses.

Since other types of studies are not always informative or even their results do not expose apparent pathology and may be within the normal range, EMIS is assigned to:

  • male infertility of unexplained genesis;
  • miscarriages in history in the early stages;
  • presence of gametes with teratozoospermia or asthenozoospermia;
  • preparation for IVF, ICSI, artificial insemination;
  • detection by results of other surveys of a decrease in the number of active gametes;
  • having multiple unproductive IVF attempts.

 

It should be noted that EMIS is not carried out in the case of azoospermia and severe oligospermia detected during the standard sperm profile. Since sometimes the main cause of impaired fertility is precisely the changes in the microstructure of male germ cells, only EMIS makes it possible to detect pathology and determine the tactics and strategy of fighting the ailment. For the study, gametes are fixed using special resins. Then a few micron sections are made, which subsequently serve as material for studying the structure of spermatozoa.

Electron-microscopic examination of spermatozoa is the most accurate diagnostic method available today, which allows to analyze and describe the internal and external structure of a cell, to determine the hidden causes of infertility and to begin an effective fight against infertility.

We recommend reading:

  • What is the price of surrogacy motherhood?What is the price of surrogacy motherhood? Gestational surrogacy motherhood is quite expensive for many families. To ease your financial burden, we have developed flexible and transparent payment options for this service provided by our company. The cost of a standard package of IVF services with embryo transfer to the uterus of the surrogat... more
  • Blood type and reproductive capacityBlood type and reproductive capacity Every couple who has trouble conceiving is wondering why this is happening. One of the first answers to this difficult question is considered the so-called group compatibility of partners. Let's try to figure out how these partners' blood parameters affect conception and successful pregnancy.A blood... more
  • Types of surrogate motherhoodTypes of surrogate motherhood Types of surrogate motherhood, their similarities and differences. What is surrogacy and who is a surrogate?Surrogacy definition is an assisted technology used in reproductive medicine. When used, the woman voluntarily agrees to endure and give birth to a child biologically not connected to her. The... more
  • What can you expect from intrauterine insemination?What can you expect from intrauterine insemination? Intrauterine insemination is historically the first method of artificial insemination. In 30s an intrauterine insemination was done during a natural cycle by injecting into the woman’s uterus the whole unprocessed semen. Intrauterine insemination is historically the first method of artificial insemi... more
  • Emotional connection with a child born by a surrogate motherEmotional connection with a child born by a surrogate mother During the life of the child, the parents are connected by strong bonds. Psychological communication awakens in the parents a calling to take care of their baby, educate it, engage in its development. It is this connection in a crisis that causes the child to instinctively seek protection from his p... more

 



Entering your comment.



* All your information is strictly confidential and will not be disclosed

Please, contact our coordinator, who will give you the detailed plan of the programme you are interested in and provide further assistance.

Entering your number, please, add your country`s code.


* All your information is strictly confidential and will not be disclosed

Наверх
Закрыть
X

If you have any questions, please, leave you phone number or email. Our consultant will keep in touch with you to answer all your questions.



For displaying of the personalized content this website uses cookies and other relevant technologies.By clicking OK or continuining using this website without changing cookies usage settings in your browser you give concent for the appliance of this technology.